Position | Host institution | PhD enrolment | Start date | Duration |
ESR5 | P3-FINCB | Y (at U Milano/Pavia) | early 2017 | 36 months |
Glia dysfunction associated to seizures and status epilepticus in animal models and humans Diogo VilaVerde |
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Methodology: Neurophysiological, histological and molecular techniques will be employed. The ESR will be trained to run in vivo video-EEG experiments on chronic animal models of temporal lobe epilepsy and in vitro experiments on brain slices and on the isolated guinea pig brain preparation. The research will compare human tissue obtained from epilepsy surgery (temporal lobe epilepsies and focal cortical dysplasias) and animal models to identify the role of seizure activity on astro/microglia activation. 7T magnetic resonance imaging studies (including DTI and high-resolution spectroscopy) of animal model and human post-surgical and experimental tissue will be used.
Marco de Curtis This email address is being protected from spambots. You need JavaScript enabled to view it.http://www.istituto-besta.it/Area-Ricerca.aspx?doc=Elenco-Unita-Operative&IdUO=UO-EPILETTOLOGIACLINICAENEUROFISIOLOGIASPERIMENTALE |