Epi Brain

Welcome to the EU-GliaPhD blog!

Here we will report on the latest developments in the field of epilepsy research.
But first, who are we?
We are a network of European neuroscientists, early stage researchers and experienced principal investigators. Our goal is to provide high quality information on epilepsy research to the public.

Our information will be mixed, i.e. targeting a lay audience, but also colleagues in the field.

Here, we start with a very recent article in which the most influential publications and journals of the last 5 to 10 years are highlighted. This set of data provides basic information where an interested person can find reliable research results.

PDF 32Epilepsy-Specific Citation Classics Revisited



+7 # Till Zimmer 2018-09-28 22:05
Good collection of literature giving an overview into the most relevant publications on epilepsy. It is important to acknowledge that epilepsy can also be targeted by attacking disease meachanisms that are common in several neurological disorders like inflammatory pathways (doi:10.1038%2Fnrneurol.2010.178 or doi:10.1111/j.1528-1167.2011.03033.x) or oxidative stress (doi:10.1093/brain/awy071 or doi:10.1093/brain/awx117). This hints towards the fact that glial cells might be key player in these processes and could be therapeutically targeted by anti-inflammatory or anti-oxidant agents!
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+8 # Vanessa Henriques 2018-09-28 17:57
Great set of data on epilepsy that can be very useful for our research!
Take a look also on the prominent involvement of astrocytes in ictogenesis, where neuron–astrocyte interaction may represent a novel target to develop effective therapeutic strategies to control seizures: https://doi.org/10.1371/journal.pbio.1000352, as well as on a description of a brain slice model
to study the generation and the propagation of focally-induced epileptiform activity: https://doi.org/10.1016/j.jneumeth.2015.04.001
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+8 # Davide Gobbo 2018-09-28 17:14
This is really a noteworthy tool for keeping an eye on the foundation stones in the field of epilepsy. Check also this review for a quick overlook on non-convulsive Childhood Absence Epilepsy: https://doi.org/10.1038/nrn811. And here again a more recent paper on the topic to keep on the track: https//doi.org/10.1038/s41593-018-0130-4
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+10 # Laura Caudal 2018-09-28 16:12
Excellent collection of epilepsy literature! Must-read for an insight into the importance of astrocyte metabolism in epilepsy and for development of therapeutic approaches: https://doi.org/10.1002/glia.23247.
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